Functional Connectivity Predicts Complex Action Deficits After Stroke

MRRI Associate Director Laurel Buxbaum, PsyD, and colleagues from MRRI and the National Institutes of Health published the results of a new study showing that abnormalities in the connections between different brain regions determine clinical symptoms.

The researchers focused on a syndrome called “apraxia” – a disorder of complex actions. Using leading-edge approaches to brain imaging analysis that enable examination of connectivity between different brain regions, they showed that the connection between left hemisphere and right hemisphere brain regions was a strong predictor of patients’ abilities. These results inform our growing understanding of the impact of single-hemisphere strokes on the functioning of the entire brain.

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