Laurel J. Buxbaum, PsyD

Associate Director
Director of Cognition and Action Laboratory
Research Professor of Rehabilitation Medicine, Thomas Jefferson University
Laurel J. Buxbaum, PsyD
Bio

Dr. Buxbaum has a longstanding interest in the cognitive neuropsychology of object, space, and body processing, and is a recognized expert in the study of action and apraxia. She received a BA in Biological Bases of Behavior from the University of Pennsylvania in 1982 and a Doctorate in Clinical Psychology (with specialization in Neuropsychology) from Hahnemann University in 1988. She completed an NIH National Research Service Award Fellowship at Moss Rehabilitation Research Institute in 1994. 

She has served as an Associate Editor of the journals Cognition and Journal of Neuropsychology, a guest Editor of Journal of the International Neuropsychological Society and Cognitive Neuroscience, and is currently an Associate Editor of Cortex. She has also served as an invited panel member at numerous national and international meetings and as a member of scientific planning committees at the National Institute of Health. 

Her laboratory has received grant funding from the National Institute of Health, National Institute of Disability and Rehabilitation Research, and the James S. McDonnell Foundation. She is the recipient of the Widener University Graduate Award for Excellence in Professional Psychology, the Maimonides Society Manuscript Award, and the Cohen Award from the Einstein Healthcare Network, and was invited to join the International Neuropsychological Symposium in 2015.

Research Interests
  • The functional neuroanatomy and functional connectivity of the action system in the healthy and damaged brain
  • Competition between actions as a source of action errors, and how such competition is modulated by cognitive control processes
  • Expanding our understanding of “grounded cognition”: the dynamic role of action in object concepts as a function of context and task
  • Plasticity of sensorimotor representations of body and space coding in the brain
  • Relationships between the language system and skilled action system
Publications
2015

Watson, C. E., & Buxbaum, L. J. (2015). A distributed network critical for selecting among tool-directed actions. Cortex65, 65-82. PMID: 25681649.
Tarhan, L. Y., Watson, C. E., Buxbaum, L. J. (In Press). Shared and distinct neuroanatomic regions critical for tool-related action production and recognition: Evidence from 131 left hemisphere stroke patients. Journal of Cognitive Neuroscience. PMID: 26351989

2014

Kalénine, S., Shapiro, A. D., Flumini, A., Borghi, A. M., & Buxbaum, L. J. (2014). Visual context modulates potentiation of grasp types during semantic object categorization. Psychonomic Bulletin & Review21(3), 645-651. PMID: 24186270
Bark, K., Hyman, E., Tan, F., Cha, E., Jax, S. A., Buxbaum, L. J., & Kuchenbecker, K. J. (2015). Effects of Vibrotactile Feedback on Human Learning of Arm Motions. Neural Systems and Rehabilitation Engineering, IEEE Transactions on23(1), 51-63. PMID: 25486644
Tsagkaridis, K., Watson, C. E., Jax, S. A., & Buxbaum, L. J. (2014). The role of action representations in thematic object relations. Frontiers in Human Neuroscience, 8, 140. PMID: 24672461
Buxbaum, L. J., Shapiro, A. D., & Coslett, H. B. (2014). Critical brain regions for tool-related and imitative actions: a componential analysis. Brain, 137(7), 1971–1985. PMID:24776969
Lee, C. I., Mirman, D., & Buxbaum, L. J. (2014). Abnormal dynamics of activation of object use information in apraxia: evidence from eyetracking. Neuropsychologia59, 13-26. PMID:24746946
Watson, C. E., & Buxbaum, L. J. (2014). Uncovering the architecture of action semantics. Journal of Experimental Psychology: Human Perception and Performance, 40(5), 1832-1848. PMID:25045905
Jax, S. A., Rosa-Leyra, D. L., & Buxbaum, L. J. (2014). Conceptual-and production-related predictors of pantomimed tool use deficits in apraxia. Neuropsychologia62, 194-201.PMID:25107676

2013

Jax, S. A., & Buxbaum, L. J. (2013). Response interference between functional and structural object‐related actions is increased in patients with ideomotor apraxia. Journal of Neuropsychology7(1), 12-18. PMID: 22515637
Binkofski, F., & Buxbaum, L. J. (2013). Two action systems in the human brain. Brain and Language127(2), 222-229. PMID: 22889467
Lee, C. L., Middleton, E., Mirman, D., Kalénine, S., & Buxbaum, L. J. (2013). Incidental and context-responsive activation of structure-and function-based action features during object identification. Journal of Experimental Psychology: Human perception and Performance39(1), 257-270. PMID: 22390294
Kalénine, S., Shapiro, A. D., Buxbaum, L. J. (2013). Processing of action means and outcome in left hemisphere stroke. Neuropsychologia, 51(7), 1224-1233. PMID: 23566892

2012

Kalenine, S., Mirman, D., & Buxbaum, L. J. (2012). A Combination of Thematic and Similarity-Based Semantic Processes Confers Resistance to Deficit Following Left Hemisphere Stroke. Frontiers in Human Neuroscience6, 106. PMID: 22586383
Kalénine, S., Mirman, D., Middleton, E. L., & Buxbaum, L. J. (2012). Temporal dynamics of activation of thematic and functional knowledge during conceptual processing of manipulable artifacts. Journal of Experimental Psychology: Learning, Memory, and Cognition38(5), 1274-1295. PMID: 22449134
Buxbaum, L. J., Dawson, A. M., & Linsley, D. (2012). Reliability and validity of the Virtual Reality Lateralized Attention Test in assessing hemispatial neglect in right-hemisphere stroke. Neuropsychology26(4), 430-441. PMID: 22642393

2011

Sathian, K., Buxbaum, L. J., Cohen, L. G., Krakauer, J. W., Lang, C. E., Corbetta, M., & Fitzpatrick, S. M. (2011). Neurological Principles and Rehabilitation of Action Disorders Common Clinical Deficits. Neurorehabilitation and Neural Repair25(5 suppl), 21S-32S. PMID: 21613535
Palluel-Germain, R., Jax, S. A., & Buxbaum, L. J. (2011). Visuo-motor gain adaptation and generalization following left hemisphere stroke. Neuroscience Letters498(3), 222-226. PMID: 21605626
Bark, K., Khanna, P., Irwin, R., Kapur, P., Jax, S. A., & Buxbaum, L. J., et al. (2011). Lessons in using vibrotactile feedback to guide fast arm motions. In Proceedings of the 2011 IEEE World Haptics Conference (pp. 355–360). IEEE.

2010

Dawson, A. M., Buxbaum, L. J., & Duff, S. V. (2010). The impact of left hemisphere stroke on force control with familiar and novel objects: Neuroanatomic substrates and relationship to apraxia. Brain Research1317, 124-136. PMID: 19945445
Myung, J. Y., Blumstein, S. E., Yee, E., Sedivy, J. C., Thompson-Schill, S. L., & Buxbaum, L. J. (2010). Impaired access to manipulation features in apraxia: evidence from eyetracking and semantic judgment tasks. Brain and Language,112(2), 101-112. PMID: 20064657
Jax, S. A., & Buxbaum, L. J. (2010). Response interference between functional and structural actions linked to the same familiar object. Cognition115(2), 350-355. PMID: 20156619
Buxbaum, L. J., & Kalénine, S. (2010). Action knowledge, visuomotor activation, and embodiment in the two action systems. Annals of the New York Academy of Sciences1191(1), 201-218. PMID: 20392282
Kalénine, S., Buxbaum, L. J., Coslett, H. B. (2010). Critical brain regions for action recognition: lesion-symptom mapping in left hemisphere stroke. Brain, 133(11), 3269-3280. PMID: 20805101

2009

Jax, S. A., Buxbaum, L. J., Lie, E., & Coslett, H. B. (2009). More than (where the target) meets the eyes: Disrupted visuomotor transformations in optic ataxia.  Neuropsychologia47(1), 230-238. PMID: 18725238
Botvinick, M. M., Buxbaum, L. J., Bylsma, L. M., & Jax, S. A. (2009). Toward an integrated account of object and action selection: a computational analysis and empirical findings from reaching-to-grasp and tool-use. Neuropsychologia47(3), 671-683. PMID: 19100758

2008

Coslett, H. B., Buxbaum, L. J., & Schwoebel, J. (2008). Accurate reaching after active but not passive movements of the hand: Evidence for forward modeling. Behavioural Neurology, 19, 117–125. PMID: 18641431
Buxbaum, L. J., Haaland, K. Y., Hallett, M., Wheaton, L., Heilman, K. M., Rodriguez, A., & Rothi, L. J. G. (2008). Treatment of limb apraxia: moving forward to improved action. American Journal of Physical Medicine & Rehabilitation87(2), 149-161. PMID: 18209511
Buxbaum, L. J., Palermo, M. A., Mastrogiovanni, D., Read, M. S., Rosenberg-Pitonyak, E., Rizzo, A. A., & Coslett, H. B. (2008). Assessment of spatial attention and neglect with a virtual wheelchair navigation task. Journal of Clinical and Experimental Neuropsychology30(6), 650-660. PMID: 18608643
Hamilton, R. H., Coslett, H. B., Buxbaum, L. J., Whyte, J., & Ferraro, M. K. (2008). Inconsistency of performance on neglect subtype tests following acute right hemisphere stroke. Journal of the International Neuropsychological Society14(1), 23-32. PMID: 18078528
Dawson, A., Buxbaum, L. J., & Rizzo, A. A. (2008). The Virtual Reality Lateralized Attention Test: Sensitivity and validity of a new clinical tool for assessing hemispatial neglect. Virtual Rehabilitation, 2008, (77–82).

2007

Buxbaum, L. J., Kyle, K., Grossman, M., & Coslett, B. (2007). Left inferior parietal representations for skilled hand-object interactions: evidence from stroke and corticobasal degeneration. Cortex43(3), 411-423. PMID: 17533764
Buxbaum, L. J., Ferraro, M., Whyte, J., Gershkoff, A., & Coslett, H. B. (2007). Amantadine treatment of hemispatial neglect: a double-blind, placebo-controlled study. American Journal of Physical Medicine & Rehabilitation86(7), 527-537. PMID: 17581287
Giovannetti, T., Schwartz, M. F., & Buxbaum, L. J. (2007). The coffee challenge: A new method for the study of everyday action errors. Journal of Clinical and Experimental Neuropsychology29(7), 690-705. PMID: 17891679
Barde, L. H., Buxbaum, L. J., & Moll, A. D. (2007). Abnormal reliance on object structure in apraxics’ learning of novel object-related actions. Journal of the International Neuropsychological Society13(6), 997-1008. PMID: 17942018

2006

Biran, I., Giovannetti, T., Buxbaum, L. J., & Chatterjee, A. (2006). The alien hand syndrome: What makes the alien hand alien?. Cognitive Neuropsychology,23(4), 563-582. PMID: 21049344
Barrett, A. M., Buxbaum, L. J., Coslett, H. B., Edwards, E., Heilman, K. M., Hillis, A. E., … & Robertson, I. H. (2006). Cognitive rehabilitation interventions for neglect and related disorders: moving from bench to bedside in stroke patients. Journal of Cognitive Neuroscience18(7), 1223-1236. PMID: 16839294
McCrea, S. M., Buxbaum, L. J., & Coslett, H. B. (2006). Illusory conjunctions in simultanagnosia: Coarse coding of visual feature location?. Neuropsychologia44(10), 1724-1736. PMID: 16643968
Buxbaum, LJ, Palermo, M, Mastrogiovanni, D, Read, MS, Rosenberg-Pitonyak, E, Rizzo, AA, Coslett, H.B. Assessment of Spatial Neglect with a Virtual Wheelchair Navigation Task. IEEE XPlore, Aug, 650-660, 2006 PMID: 18608643
Jax, S. A., Buxbaum, L. J., & Moll, A. D. (2006). Deficits in movement planning and intrinsic coordinate control in ideomotor apraxia. Journal of Cognitive Neuroscience18(12), 2063-2076. PMID: 17129191
Buxbaum, L. J., Kyle, K. M., Tang, K., & Detre, J. A. (2006). Neural substrates of knowledge of hand postures for object grasping and functional object use: Evidence from fMRI. Brain Research1117(1), 175-185. PMID: 16962075

2005

Giovannetti, T., Buxbaum, L. J., Biran, I., & Chatterjee, A. (2005). Reduced endogenous control in alien hand syndrome: evidence from naturalistic action. Neuropsychologia43(1), 75-88. PMID: 15488908
Buxbaum, L. J., Johnson-Frey, S. H., & Bartlett-Williams, M. (2005). Deficient internal models for planning hand–object interactions in apraxia. Neuropsychologia43(6), 917-929. PMID: 15716162
Boronat, C. B., Buxbaum, L. J., Coslett, H. B., Tang, K., Saffran, E. M., Kimberg, D. Y., & Detre, J. A. (2005). Distinctions between manipulation and function knowledge of objects: evidence from functional magnetic resonance imaging. Cognitive Brain Research23(2-3), 361-373. PMID: 15820643
Buxbaum, L. J., Kyle, K. M., & Menon, R. (2005). On beyond mirror neurons: Internal representations subserving imitation and recognition of skilled object-related actions in humans. Cognitive Brain Research25(1), 226-239. PMID: 15996857

Selected Publications Prior to 2005

Buxbaum, L. J., Giovannetti, T., & Libon, D. (2000). The role of the dynamic body schema in praxis: Evidence from primary progressive apraxia. Brain and Cognition44(2), 166-191. PMID: 11041988
Buxbaum, L. J., & Saffran, E. M. (2002). Knowledge of object manipulation and object function: dissociations in apraxic and nonapraxic subjects. Brain and Language82(2), 179-199. PMID: 12096875
Buxbaum, L. J., Schwartz, M. F., & Carew, T. G. (1997). The role of semantic memory in object use. Cognitive Neuropsychology14(2), 219-254. PMID: 19482039
Buxbaum, L. J., Sirigu, A., Schwartz, M. F., & Klatzky, R. (2003). Cognitive representations of hand posture in ideomotor apraxia. Neuropsychologia41(8), 1091-1113. PMID: 12667544
Pavese, A., & Buxbaum, L. J. (2002). Action matters: The role of action plans and object affordances in selection for action. Visual Cognition9(4-5), 559-590.