Dylan Edwards, PhD

Director, Moss Rehabilitation Research Institute

Director, Laboratory for Stroke Motor Recovery

Dylan Edwards, PhD
Bio

Dr. Edwards recently joined MRRI from Burke Neurological Institute in White Plains, N.Y., where he was the director of the Non-Invasive Brain Stimulation Laboratory and director of the Restorative Neurology Clinic. He was also a lecturer in neurology, and Co-Director of the Intensive Course in Transcranial Magnetic Stimulation at Harvard Medical School.  Dr. Edwards holds a position as professor in neuroscience, at Edith Cowan University in Australia.

Dr. Edwards’ research focuses on using technology, including transcranial magnetic stimulation and rehabilitation robotics, to improve recovery in stroke, cerebral palsy and spinal cord injury. At MRRI, he will lead additional development of clinical-research integration, and will further expand MRRI’s movement science focus.

The newly created Laboratory for Stroke Motor Recovery will have several lines of research addressing recovery of functional movement in humans following stroke. Quantitative clinical neurophysiology, neuroimaging and kinematic data will be studied to understand the basis of motor symptoms, and inform emerging physical rehabilitation strategies.

Publications
2019

Yu S, Perez H, Barkas J, Mohamed M, Eldaly M, Huang TH, Yang X, Su H, del Mar Cortes M, Edwards DJ: A soft high force hand exoskeleton for rehabilitation and assistance of spinal cord injury and stroke individuals. Proceedings of the 2019 Design of Medical Devices Conference DMD2019

Buchwald, A., Calhoun, H., Rimikis, S., Lowe, M., Wellner, R., Edwards DJ. (2019) Using tDCS to facilitate motor learning in speech production: The role of timing. Cortex 111: 274-285. doi.org/10.1016/j.cortex.2018.11.014.

Wortman-Jutt S, Edwards D. Poststroke Aphasia Rehabilitation: Why All Talk and No Action? Neurorehabilitation and Neural Repair (in press) 2019

Gerber, M., McLean, A., Stephen, S., Chalco, A., Arshad, U. … Edwards, DJ. NeuroMeasure: a software package for quantification of cortical motor maps using frameless stereotaxic transcranial magnetic stimulation. Frontiers in Neuroinformatics (Provisionally accepted).

Wortman-Jutt, S., & Edwards, DJ. Post-Stroke Aphasia Rehabilitation: Why All Talk and No Action? Neurorehabilitation and Neural Repair (Provisionally accepted).

Gerber MB, McLean AC, Stephen SJ, Chalco AG, Arshad UM, Thickbroom G, Silverstein J, Tsagaris Z, Kuceyeski A, Friel K, Santos TEG, Edwards DJ. NeuroMeasure: a software package for quantification of cortical motor maps using frameless stereotaxic transcranial magnetic stimulation, Frontiers in Neuroinformatics (accepted)

Edwards D, et al. Clinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS. Restorative Neurology and Neuroscience (accepted)

2017

Kim Y, Ngo JP, Deblieck C, Edwards DJ, Dobkin B, Wu AD, Iacoboni M. (2017) Individual level reliability of PAS-induced neural plasticity. bioRxiv (In Review). 

2015

Thickbroom GW, Cortes M, Rykman A, Volpe BT, Fregni F, Krebs HI, Edwards DJ. (2015) Stroke subtype and motor impairment influence contralesional excitability. Neurology, 85(6):517-520.

2013

Edwards DJ, Cortes M, Datta A, Minhas P, Wassermann EM, Bikson M. (2013) Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: A basis for high-definition tDCS. Neuroimage, 74:266-275. doi: 10.1016/j.neuroimage.2013.01.042.

2012

Conesa L, Costa U, Morales E, Edwards DJ, Cortes M, León D, Bernabeu M, Medina J (2012) An observational report of intensive robotic and manual gait training in sub-acute stroke. J Neuroeng Rehabil, 9:13. doi: 10.1186/1743-0003-9-13.

Benito-Penalva J, Edwards DJ, Opisso E, Cortes M, Lopez-Blazquez R, Murillo N, Costa U, Tormos JM,  Vidal-Samsó J, Valls-Solé J, Medina J. (2012) European Multicenter Study about Human Spinal Cord Injury Study Group, Medina J. (2012) Gait training in human spinal cord injury using electromechanical systems: effect of device type and patient characteristics. Arch Phys Med Rehabil, 93(3):404-12.

Brunoni AR, Nitsche MA, Bolognini N, Bikson M, Wagner T, Merabet L, Edwards DJ, Valero-Cabre A, Rotenberg A, Pascual-Leone A, et al. (2012) Clinical research with transcranial direct current stimulation (tDCS): Challenges and future directions. Brain Stimul, 5(3):175-195.

2011 

Cortes M, Thickbroom GW, Valls-Sole J, Pascual-Leone A, Edwards DJ. (2011) Spinal associative stimulation: A non-invasive stimulation paradigm to modulate spinal excitability. Clin Neurophysiol, 122(11):2254-2259. doi: 10.1016/j.clinph.2011.02.038 (see also Editorial, Clin Neurophys).

Giacobbe V, Volpe BT, Thickbroom GW, Fregni F, Pascual-Leone A, Krebs HI, Edwards DJ. (2011) Reversal of TMS-induced motor twitch by training is associated with a reduction in excitability of the antagonist muscle. Journal Of Neuroengineering And Rehabilitation, 8:46. doi: 10.1186/1743-0003-8-46.

Najib U, Bashir S, Edwards DJ, Rotenberg A, Pascual-Leone A. (2011) Transcranial Brain Stimulation: Clinical Applications and Future Directions. Neurosurg Clin N Am, 22(2):233-51.

Bashir S, Edwards DJ, Pascual-Leone A. (2011) Neuronavigation Increases the Physiologic and Behavioral Effects of Low-Frequency rTMS of Primary Motor Cortex in Healthy Subjects Brain Topogr, 24(1):54-64.

2010

Kumru H, Murillo N, Vidal Samso J, Valls-Sole J, Edwards DJ, Pelayo R, Valero-Cabre A, Tormos JM,  Pascual-Leone A. (2010) Reduction of Spasticity With Repetitive Transcranial Magnetic Stimulation in Patients With Spinal Cord Injury. Neurorehabil Neural Repair, 24(5)435-441. doi: 10.1177/1545968309356095.

Chye L, Nosaka K, Murray L, Edwards DJ, Thickbroom GW. (2010) Corticomotor excitability of wrist flexor and extensor muscles during active and passive movement. Hum Mov Sci, 29(4):494-501. doi: 10.1016/j.humov.2010.03.003.

2009 

Boggio PS, Amancio EJ, Correa CF, Cecilio S, Valasek C, Bajwa Z, Freedman SD, Pascual-Leone A, Edwards DJ, Fregni F. (2009) Transcranial DC stimulation coupled with TENS for the treatment of chronic pain: a preliminary study. Clin J Pain, 25(8):691-695. doi: 10.1097/AJP.0b013e3181af1414

Boggio P, Santos C, Fernandes Correa C, Amancio E, Freedman S, Pascual-Leone A, Edwards DJ, Fregni F. (2009) Transcranial DC stimulation coupled with TENS for the treatment of chronic pain. Clin J Pain, 25(8):691-5.

Volpe BT, Huerta PT, Zipse JL, Rykman A, Edwards DJ, Dipietro L, Hogan N, Krebs HI. (2009) Robotic devices as therapeutic and diagnostic tools for stroke recovery. Arch Neurol, 66(9):1086-1090.

LG Johnson, KE Collier, DJ Edwards, DL Philippe, PR Eastwood, SE Walters, GW Thickbroom, FL Mastaglia (2009) Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis. J Clinical Neuromuscular Disease, 10(4):178-84.

Edwards DJ, et al., (2009) Raised corticomotor excitability of M1 forearm area following anodal tDCS is sustained during robotic wrist therapy in chronic stroke. Restor Neurol Neurosci, 27(3):199-207.

2008 

Chapman DW, Needham KJ, Allison GT, Lay B, Edwards DJ. (2008) Effects of experience in a dynamic environment on postural control. Br J Sports Med, 42(1):16-21.

Chapman DW, Needham KJ, Allison GT, Lay B, Edwards DJ. (2008). Effects of experience within a dynamic environment on postural control. Br J Sports Med, 42(1):16-21.

2007

Johnson LG, Edwards DJ, Walters S, Thickbroom GW, Mastaglia FL. (2007) The effectiveness of an individualized, home-based functional exercise program for patients with sporadic inclusion body myositis. J Clinical Neuromuscular Disease June, 8(4):187-194.

Edwards DJ, Mastaglia FL, Byrnes ML, Fregn F, Pascual-Leone A, Thickbroom GW. (2007) Supraspinal inputs reduce corticomotor excitability during passive movement: evidence from a pure sensory stroke. Restor Neurol Neurosci, 25(5-6):527-533.

2006

Rodrigues JP, Edwards DJ, Walters SE, Byrnes ML, Thickbroom GW, Stell R, Mastaglia FL. (2006) Blinded placebo crossover study of gabapentin in primary orthostatic tremor. Mov Disord, 21(7):900-905.

Thickbroom GW, Byrnes ML, Edwards DJ, Mastaglia FL. (2006). Repetitive paired-pulse TMS at I- wave periodicity markedly increases corticospinal excitability: a new technique for modulating synaptic plasticity. Clin Neurophysiology, 117(1):61-66.

McGuigan MR, Doyle TLA, Newton M, Edwards DJ, Nimphius S, Newton RU. (2006) Eccentric Utilization Ratio: Effect of Sport and Phase of Training. The Journal of Strength and Conditioning Research, 20(4):992–995.

2005

Rodrigues JP, Edwards DJ, Walters S, Byrnes ML, Thickbroom GW, Stel R, Mastaglia FL (2005). Gabapentin can improve postural stability and quality of life in Primary Orthostatic Tremor. Movement Disorders, 20(7):865-886.

2004

Edwards DJ, Thickbroom GW, Byrnes ML, Ghosh S, Mastaglia FL. (2004). Temporal aspects of passive movement-related corticomotor inhibition. Hum Mov Sci, 23(3-4):379-387.

2002

Edwards DJ, Thickbroom GW, Byrnes ML, Ghosh S, Mastaglia, FL. (2002) Reduced corticomotor excitability with cyclic passive movement: a study using transcranial magnetic stimulation. Hum Mov Sci, 2(5-6):533-540.