Dylan J. Edwards, PhD

Director, Moss Rehabilitation Research Institute

Director, Laboratory for Stroke Motor Recovery

Dylan J. Edwards, PhD
Bio

Dr. Edwards recently joined MRRI from Burke Neurological Institute in White Plains, N.Y., where he was the director of the Non-Invasive Brain Stimulation Laboratory and director of the Restorative Neurology Clinic. He was also a lecturer in neurology, and Co-Director of the Intensive Course in Transcranial Magnetic Stimulation at Harvard Medical School.  Dr. Edwards holds a position as professor in neuroscience, at Edith Cowan University in Australia.

Dr. Edwards’ research focuses on using technology, including transcranial magnetic stimulation and rehabilitation robotics, to improve recovery in stroke, cerebral palsy and spinal cord injury. At MRRI, he will lead additional development of clinical-research integration, and will further expand MRRI’s movement science focus.

The newly created Laboratory for Stroke Motor Recovery will have several lines of research addressing recovery of functional movement in humans following stroke. Quantitative clinical neurophysiology, neuroimaging and kinematic data will be studied to understand the basis of motor symptoms, and inform emerging physical rehabilitation strategies.

Publications

Below are selected publications by Dr. Edwards. For a full list of his published research, click here.

2019

Edwards DJ, Cortes M, Rykman-Peltz Otr  A, Chang J, Elder J., … Pascual-Leone, (2019) A. Clinical improvement with intensive robotic arm training in chronic stroke is unchanged by supplementary tDCS. Restor Neurol Neurosci 37(2) 167-180; doi:10.3233/RNN-180869. PMID: 30932903.

Buchwald, A., Calhoun, H., Rimikis, S., Lowe, M., Wellner, R., Edwards DJ. (2019) Using tDCS to facilitate motor learning in speech production: The role of timing. Cortex 111: 274-285. doi.org/10.1016/j.cortex.2018.11.014. PMID: 30551048.

Wortman-Jutt S, Edwards D. (2019) Poststroke Aphasia Rehabilitation: Why All Talk and No Action? Neurorehabilitation and Neural Repair, Volume 33, Issue 4. PMID: 30900528.

Gerber MB, McLean AC, Stephen SJ, Chalco AG, Arshad UM, Thickbroom G, Silverstein J, Tsagaris Z, Kuceyeski A, Friel K, Santos TEG, Edwards DJ. (2019) NeuroMeasure: a software package for quantification of cortical motor maps using frameless stereotaxic transcranial magnetic stimulation, Frontiers in Neuroinformatics 13:23. doi: 10.3389/fninf.2019.00023. PMID: 31105546.

Cramer SC, Dodakian L, Le V, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, et al.; National Institutes of Health StrokeNet Telerehab Investigators. (2019) Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke: A Randomized Clinical Trial. JAMA Neurol. Jun 24. doi: 10.1001/jamaneurol.2019.1604. PMID: 31233135.

 2018

Harvey, R.L., Edwards, D.J., Dunning, K., Fregni, F., Stein, J., Laine, J., Rogers, L.M., Vox, F., Durand-Sanchez, A., Bockbrader, M., Goldstein, L.B., Francisco, G.E., Kinney, C.L., Liu, C.Y.: NICHE Trial Investigators. (2018) Randomized Sham-Controlled Trial of Navigated Repetitive Transcranial Magnetic Stimulation for Motor Recovery in Stroke. Stroke 49(9):2138-2146. doi: 10.1161/STROKEAHA.117.020607. PMID: 30354990.

Santos, T., Favoretto, D.B., Toostani, I.G., Nascimento, D., Rimoli, B.P., Bergonzoni, E., Lemos, J.W., Truong, D.Q., DElbem, A.C.B., Makkiabadi, B., Mores, R., Louzada, F., Aikson, M., Leite, J.P., Edwards, D.J. (2018) Manipulation of human verticality using high-definition transcranial direct current stimulation. Frontiers in Neurology 9. doi: 10.3389/fneur.2018.00825. PMID: 30459697.

Buckwald, A., Falconer, C., Rykman-Peltz, A., Cortes, M., Pascual-Leone, A., Thickbroom, G.W., Krebs, H.I., Frengi, F., Gerger, L.M., Oromendia, C., Chang, J., Volpe, B.T., Edwards, D.J. (2018)  Robotic arm rehabilitation in chronic stroke patients with aphasia may promote speech and language recovery (but effect is not enhanced by supplementary tDCS). Frontiers in Neurology doi: 10.3389/fneur.2018.00853 PMID: 30405512.

Bikson, M., Brunoni, A., Charvet, L., Clark, V., Cohen, L., Deng, Z., Dmochowski, J., Edwards, D.J., Frohlich, F., Emily, K.. (2018) Rigor and Reproducibility in Research with Transcranial Electric Stimulation: An NIMH Workshop Report. Brain Stimulation 11(3):465-480. doi: 10.1016/j.brs.2017.12.008. PMID: 29398575

Babyar, S., Santos, T., Will-Lemos, T., Mazin, S., Edwards, D., Reding, M. (2018) Sinusoidal Transcranial Direct Current Versus Galvanic Vestibular Stimulation for Treatment of Lateropulsion Poststroke. Journal of Stroke and Cerebrovascular Diseases 27(12):3621-3625. doi: 10.1016/j.jstrokecerebrovasdis. PMID: 30314762

2017

Cortes, M., Thickbroom, G., Valls-Sole, J., Shirvalkar, P., Pascual-Leone, A., Edwards, D.J. (2017)  Improving lower limb strength in incomplete spinal cord injury with non-invasive spinal associative stimulation. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation 10(2):538–539.

Cortes M, Thickbroom G, Elder J, Rykman A, Valls-Sole J, … Edwards DJ. (2017). The corticomotor projection to liminally-contractable forearm muscles in chronic spinal cord injury: A transcranial magnetic stimulation study. Spinal Cord, 55(4), 362-366. PMID: 27995943.

Wortman-Jutt, S., Edwards, D.J. (2017) Transcranial Direct Current Stimulation in Poststroke Aphasia Recovery. Stroke 48(3):820-826. PMID: 28174328

Leon, D., Cortes, M., Elder, J., Kumru, H., Laxe, S., Edwards, D.J., Josep, M.. Montserrat-Bernabeu, T., Pascual-Leone, A. (2017) tDCS does not enhance the effects of robot-assisted gait training in patients with subacute stroke. Restorative Neurology and Neuroscience 35(4), 377-384, 2017 doi: 10.3233/RNN-170734. PMID: 28697574.

Ruffini, G., Fox, M.D., Santarnecchi, E., Miranda, P.C., Edwards, D.J., Wendling, F. (2017) Modeling, targeting and optimizing multichannel transcranial current stimulation (tCS). Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation 10(2):466-467.

 2016

Peters H, Edwards DJ, Wortman-Jutt S, Page S. (2016). Moving forward by stimulating the brain: Transcranial direct current stimulation in post-stroke hemiparesis. Front Hum Neurosci, 10(394). PMID: 27555811.

T Santos-Pontelli, T.E., Rimoli, B.P., Favoretto, D.B., Mazin, S.C., Truong, D.Q., Leite, J.P., Pontes-Neto, O.M., Babyar, S.R., Reding, M., Bikson, M., Edwards, D.J. (2016) Polarity-Dependent Misperception of Subjective Visual Vertical during and after Transcranial Direct Current Stimulation (tDCS). PLoS One, 11(3), 2016 e0152331. doi: 10.1371/journal.pone.0152331. PMID: 27031726.

Babyar, S., Santos-Pontelli, T., Will-Lemos, T., Mazin, S., Bikson, M., Truong, D.Q., Edwards, D.J., Reding, M. (2016)  Center of Pressure Speed Changes with tDCS Versus GVS in Patients with Lateropulsion after Stroke. Brain Stimulation 9(5):796-8. doi: 10.1016/j.brs.2016.06.053. PMID: 27372843.

Bolognini, N., Russo, C., Edwards, D.J.: The sensory side of post-stroke motor rehabilitation. Restorative Neurology and Neuroscience 11;34(4):571-86, 2016 doi: 10.3233/RNN-150606.

Bashir, S., Vernet, M., Najib, U., Perez, J., Alonso-Alonso, M., Knobel, M., Yoo, W.K, Edwards, D.J., Pascual-Leone, A. (2016)  Enhanced motor function and its neurophysiological correlates after navigated low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in stroke. Restorative Neurology and Neuroscience 34(4):677-789. doi: 10.3233/RNN-140460. PMID: 27567763.

2015

Thickbroom GW, Cortes M, Rykman A, Volpe BT, Fregni F, Krebs HI, Edwards DJ. (2015) Stroke subtype and motor impairment influence contralesional excitability. Neurology, 85(6):517-520. PMID: 26187228.

M Cortes, GW Thickbroom, A Rykman, A Pascual-Leone, DJ Edwards. Physiologic mapping and modeling of motor targets for neuromodulation in spinal cord injury. (2015) Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation. 8(2):431-432. doi: 10.1016/j.brs.2015.01.376

Murray, L.M., Edwards, D.J., Ruffini, G., Labar, D., Stampas. A., Pascual-Leone, A., Cortes, M. (2015)  Intensity dependent effects of transcranial direct current stimulation on corticospinal excitability in chronic spinal cord injury. Archives of Physical Medicine and Rehabilitation 96(4 Suppl):S114-21. doi: 10.1016/j.apmr.2014.11.004. PMID: 25461825.

Schambra, H.M., Ogden, R.T., Martínez-Hernández, I.E., Lin, X., Chang, Y.B., Rahman, A., Edwards, D.J., Krakauer, J.W. (2015)  The reliability of repeated TMS measures in older adults and in patients with subacute and chronic stroke. Front Cell Neuroscience, 9:335. doi: 10.3389/fncel.2015.00335. PMID: 26388729.