Mapping the Brain’s Tool Use Network

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Imagine attempting to find an everyday kitchen item—for example, a spatula— in a drawer, and then using the spatula to flip a pancake. What if instead of retrieving the spatula, you picked up and used a nearby fork with a spatula-like action? Such errors, in which objects are mis-used during the course of everyday actions, are experienced by thousands of individuals with a disabling and common disorder known as limb apraxia.

For more than two decades, the Cognition and Action Lab at MRRI, headed by Laurel Buxbaum, PsyD, has been making strides in understanding both the neurological deficits and regions of the brain involved in this disorder, as well as the normal cognitive mechanisms that permit successful tool-related actions. Among the lab’s many achievements is the development of a cognitive neuroanatomical model of the processes and brain regions that may govern complex tool-related behaviors. Continue Reading



MRRI’s Virtual Reality Tool Helps Assess Hemispatial Neglect

People who have suffered a stroke to the brain’s right hemisphere may struggle with problems related to vision and space perception, mood, energy and recognition of their own difficulties. This cluster of deficits is called right hemisphere stroke syndrome.

Laurel J. Buxbaum, PsyD, and her team at the Moss Rehabilitation Research Institute developed an improved method for testing and treating patients for hemispatial neglect after a stroke using virtual reality.

In this new video, Dr. Buxbaum explains how patients at MossRehab’s Right Hemisphere Stroke Center are benefiting from this state-of-art tool. Continue Reading


Exploring Questions Around Phantom Limb Pain

Laurel J. Buxbaum, PsyD

Laurel J. Buxbaum, PsyD

Limb amputation is a common problem affecting the brain’s representation of the body. Most individuals with amputation have a phantom limb with which they experience touch and pain. Laurel J. Buxbaum, PsyD, and colleagues in MRRI’s Cognition and Action Laboratory are performing experiments with people experiencing phantom limb sensations that will explore two major questions. Continue Reading


MRRI Testing Post-Concussion Smart Phone App

There are two major challenges in concussion management:

  1. There is no way to identify which patients will experience persistent problems, and
  2. No evidenced-based treatments are available for these patients.

Treatment development is hampered by the dearth of prognostic markers, hence the first problem contributes to the latter.

Amanda Rabinowitz, PhD, director of the Brain Injury Neuropsychology Laboratory at the Moss Rehabilitation Research Institute, is conducting a research study that uses mobile app technology to address this issue. Continue Reading